Helix Diagnostics
More Answers From One Test. Powered by AI and Real-World Evidence.
Deliver deeper insights and address multiple clinical questions with a single sample. Access flexible test options backed by our proprietary AI-enabled Clinical Interpretation engine, Helix Wayfinder™ that incorporates real-world evidence (RWE) and our unique Sequence Once, Query Often® platform. Obtain definitive answers that support improved patient outcomes and elevate your approach to personalized care.
Learn more about our genetic tests
Ongoing access to easier, faster and more dynamic, clinically indicated genetic insights to improve your ability to take a personalized genomics approach to every patient's care.
Hereditary Cancer
Understand how your patient’s genetics may facilitate preventative interventions and early detection, as well as identify at-risk family members.
Hereditary Cardiovascular
Understand how your patient’s genetics may inform the diagnosis and management of cardiovascular disorders.
Pharmacogenomics
Understand drug efficacy and the risk of side effects based on your patient’s genetic profile in order to determine optimal prescriptions.
Proactive Screening
Understand how your patient's genes could impact their health so they can be proactively monitored or receive preventive care before developing a serious condition.
Targeted Analyses
Understand your patient's risk for known conditions by evaluating specific, predefined genetic variants, enabling focused interventions and personalized care.
Precision Diagnostics, Scalable Solutions
Our approach goes beyond traditional genetic testing. We offer a scalable platform that grows with your needs, whether you're an independent practice or a large health system.
Solving Today’s Questions. Charting Tomorrow’s Paths.
Our platform delivers more than genetic results—it provides actionable answers and insights analyzed with AI and collected through the Helix Research Network® (HRN). With real-world evidence at its core, flexible testing options, and the ability to unlock new insights from a single sample over time, we help providers and health systems in their efforts to advance care today while planning for tomorrow.
Powered by AI and Real-World Evidence
Our proprietary AI-enabled Clinical Interpretation engine, Helix Wayfinder™ incorporates real-world evidence collected through the Helix Research network to translate complex data into clinical insights for health system partners.
One Sample for Life
We sequence the full exome up front, so future clinical tests can be ordered, with patient consent, without the need for a new sample. In many cases, additional results can be returned within minutes—supporting proactive, personalized care as clinical questions evolve.
Flexible, Comprehensive Testing Options
Our menu includes both single-gene tests and focused panels, making it easy to tailor testing to individual patients or broader population health goals—all from one platform that grows with your needs.
From Uncertain to Actionable.
Unlike RNA approaches limited to single samples, Helix’s methodology is powered by advanced machine learning models built from more than 184,000 high-quality variants across the genome. By accounting for relatedness, ancestry, and population stratification, Helix enables scalable, AI-driven insights across oncology, cardiovascular care, pharmacogenomics, and beyond.
Clarity Gained
In a new preprint, Helix Wayfinder™ surfaced evidence supporting reclassification for 30%+ of VUS carriers, with rates reaching 50% in genes like LDLR.
Beyond RNA
It achieved a 60% reassignment rate for splice variants, significantly outperforming RNA-based methods.
Expanding Potential
With continued dataset growth, Helix anticipates the ability to reclassify 50%+ of all VUS carriers as the Helix Research Network expands toward 3M individuals.
Partnering for Genomic Integration Success
We work closely with healthcare providers to ensure smooth implementation and ongoing success of genomic diagnostics in clinical practice.
Tailored Implementation
We assess your specific needs and design an integration plan that aligns with your clinical goals and existing workflows.
Comprehensive Education
Our team provides thorough training and support, ensuring your staff is confident in interpreting and applying genomic insights.
Seamless EHR & Portal Options
We ensure genomic data is readily accessible for you how you want it, supporting informed decision-making at the point of care.
Ongoing Clinical Support
Our team of genetic experts is available for consultation, helping you navigate complex cases and maximize the utility of genomic information.
Built For The Future
Our AI-enabled framework is powering new frontiers in genomic medicine. We are also developing large language model (LLM) capabilities to capture more nuanced patient histories from health records, unlocking even greater precision in genetic association studies.
A Selection of Our Partners
