Power Precision Medicine at Scale.
The Helix Research Network® is a large-scale scientific study designed to deepen our understanding of the relationship between genetics, environment, and health outcomes — rapidly translating findings into clinical practice.
- Vast clinico-genomic database — Pairing a vast repository of genomic data with longitudinal health information from diverse populations.
- Statistical power at scale — Uncovering subtle genetic influences on complex diseases with population-scale datasets.
- Rapid clinical translation — Rapidly translating research findings into clinical practice for more precise diagnoses and targeted treatments.
- Collaborative platform — Driving groundbreaking research across a wide range of conditions through collaborative partnerships.
Leverage collective genomic intelligence
The Helix Research Network empowers health systems to leverage collective genomic intelligence, advancing precision medicine and enhancing patient care. Our collaborative approach addresses clinical excellence, market strategy, and data-driven insights.
Support Clinical Excellence and Patient-Centered Care
Identify at-risk patients sooner, personalize treatment plans, and support improved health outcomes across your organization.
Set the Standard for Advanced Care
Build a reputation for excellence through genomics recognized by providers and patients alike, and open the doors to cutting-edge research opportunities.
Unlock the Potential of Genomic Data
Build a robust clinico-genomic knowledge base to address the unique health needs and create targeted programs for your diverse patient populations.
Sequence Once, Query Often®
Helix's unique approach accelerates speed to clinical value and patient insights. One sample becomes a lifetime of queryable data.
CLIA/CAP Accredited Lab
Proprietary Exome+® assay and advanced analytics capabilities enable rapid results delivery — from weeks to hours or even minutes.
End-to-End Partnership
From strategy to implementation to measurable impact, Helix partners with you at every step of your genomic integration journey.
Population-scale RWE that makes results more actionable
Real-world evidence (RWE) from the Helix Research Network, built on Exome+® sequencing across 400,000+ participants across ~20 health systems, enables us to resolve variants of uncertain significance (VUS) that would leave clinicians and patients without clear answers in other settings.
With every new patient sequenced, the evidence base deepens, making results more definitive and actionable for each next patient. The Helix approach to genomics is a continuously improving evidence engine — and every partner and provider not only benefits from that engine, they help it evolve.
of VUS carriers in the general population can now have their variant status resolved
of reclassified variants are confirmed Benign — giving patients clarity and peace of mind
overall increase in pathogenic (P/LP) calls — more patients receiving definitive, actionable results
projected VUS resolution as the dataset grows toward 2 million participants
End-to-end strategy. Seamless integration.
Our end-to-end strategy ensures a seamless integration of genomics into your health system's operations and future plans.
Tailored Genomic Strategy
We work with you to create a tailored genomic strategy that aligns with your organizational goals and addresses your unique challenges and opportunities.
Sustainable Implementation Model
Our team helps implement and optimize clinical workflows with pathways that ensure smooth integration of genomic data into your existing processes.
Seamless Program Launch
Leverage our advisors' expertise for rapid scaling and smooth deployment, with best practices and KPI tracking to ensure success.
Measurable Clinical Impact
Leverage genomic insights to improve patient outcomes, enhance preventive care, and optimize treatment plans across specialties.
Efficient, Scalable Sequencing
Use Helix's Exome+ platform for efficient sequencing and the proprietary Sequence Once, Query Often® model for ongoing value.
Get to clinical value faster
One of our academic health system partners made a bet on precision medicine as an enterprise strategy, not just siloed genetic testing programs. After three years, the results are in:
- PGx turnaround dropped from 1 week to 80 seconds on average using our Sequence Once, Query Often™ (SOQO) model
- 9% of patients in the program were new to the health system
- 20% of program participants hadn't seen a physician at the partner organization in 3+ years, re-engaged in their health through genomic results
- $13.5M in grant funding potential supported by the population genomics dataset
Hear from our partners
Health system leaders across the country are leveraging the Helix Research Network to transform patient care, accelerate genomic discovery, and build precision medicine programs that deliver measurable impact.
See our population genomics partners.
Trusted by leading health systems
Ready to join the network?
Empower your health system to drive precision medicine initiatives, improve patient outcomes, and lead in healthcare innovation.