The Healthy Nevada Project, created by the Renown Institute for Health Innovation (IHI), is a clinical study offering free genetic testing to residents of Nevada. This study aims to create a robust set of data—genomics, medical, and environmental—that enables researchers at Renown Health and the Desert Research Institute to advance the standard of care in Nevada and the nation as a whole. Participants in this study are given insights about their genetic ancestry and the potential influence of their DNA on certain wellness traits; among those who opt-in to receiving potentially medically relevant information, some participants will also learn about their genetic predispositions for certain diseases linked to heart disease and various cancers.

Mayo Clinic is creating a library of genomic sequencing data on 100,000 consented Mayo Clinic participants to advance research and patient care. Participants’ DNA will be sequenced using Helix’s Exome+ assay. Participants in this study, known as Tapestry, will receive genetic screening results for three highly actionable hereditary conditions that often go unrecognized, including familial hypercholesterolemia (FH), hereditary breast and ovarian cancer (BRCA1 and BRCA2), and Lynch syndrome, a form of hereditary colorectal cancer. Over time, results will be returned to Tapestry participants as well as their Mayo Clinic provider. This will allow Mayo Clinic to evaluate the benefits of Exome+ sequencing and the short- and long-term impact on health-related outcomes, health care utilization, and physician acceptance.

WholeMe is the first study of its kind to take root in Florida. In partnership with Helix, AdventHealth aims to sequence DNA from 10,000 Floridians in an effort to better prevent, diagnose, and treat diseases. Their goal is to learn how genetic information can be successfully used to advance the standard of care in Florida while also empowering participants with a combination of fun insights about their DNA and, in some cases, potentially life-saving information. AdventHealth believes knowledge is power and they want you to feel in control. To feel empowered. To feel whole.

The Genobank Project is a large-scale study seeking to collect genetic data from ethnically diverse individuals with the ultimate goal of learning more about the ways in which our DNA may affect health and contribute to disease development—including diseases that disproportionately affect minority communities. Each participant is sequenced using Helix’s Exome+ assay and this data is then used for groundbreaking research. Additionally, participants may consent to receive a free genetic report detailing their genetic ancestry and more.

The Medical University of South Carolina (MUSC) is joining the latest wave of population genomics programs, and partnering with Helix to launch In Our DNA SC. The large-scale (100,000 participant) program is designed to improve health care outcomes by integrating genetic insights into clinical care and research. MUSC will leverage Helix’s unique Sequence Once, Query Often model and its end-to-end integration platform to enable immediate clinical application and continual on-demand use of genetic insights throughout a patient’s life. The robust clinico-genomic dataset developed from consenting participants will also be used to pioneer and further advance genomics research.

HealthPartners has launched myGenetics, a population genomics program that will provide important healthinformation to families across Minnesota and surrounding states. As a large-scale community health research program, myGenetics has partnered with Helix to better understand how DNA impacts health and how it may be used to provide more personalized care to HealthPartners patients. The program aligns with HealthPartners ongoing drive to deliver simple, personalized, affordable care while advancing precision medicine and greater health equity.The myGenetics program is available to HealthPartners patients over the age of 18 and aims to enroll more than 100,000 participants over four years.

Memorial Hermann Health System will be launching a population genomics research program designed to utilize DNA information to look for hidden health risks. Information will be used to help the health system better understand the health of its overall population and will give patients and their providers insight into their health in order to personalize patient care and create proactive care plans to address key risk factors. It will have an anticipated 100,000 participants and will be one of the largest population health research programs in Texas. The program will be used by Memorial Hermann to redefine health care for the communities the system has served for more than 115 years.

WellSpan Health is launching a comprehensive population genomics program designed to improve patient healthcare outcomes by integrating genetic insights into clinical care and research. The genetic reports made available by this program may allow patients and their health providers to develop precision health care plans to proactively mitigate serious health risk conditions and take a more preventative and individualized approach to their care. Wellspan will leverage Helix’s end-to-end genomic platform and unique Sequence Once, Query Often™ model. This allows the opportunity to run future tests that provide new and ongoing health insights without the need to collect additional genetic samples from each patient.