Genomics made simple for the clinicians who need it most
Helix removes the complexity from genetic testing so you can focus on what matters — caring for your patients. Order tests, receive actionable results, and close care gaps, all within your existing workflow.
Population-scale RWE that helps inform clinical interpretation of results
Real-world evidence (RWE) from the Helix Research Network®, built on Exome+® sequencing across 400,000+ participants across ~20 health systems, enables us to resolve variants of uncertain significance (VUS) that would leave clinicians and patients without clear answers in other settings.
With every new patient sequenced, the evidence base deepens, making results more definitive and actionable for each next patient. The Helix approach to genomics is a continuously improving evidence engine — and every partner and provider not only benefits from that engine, they help it evolve.
of VUS carriers in the general population can now have their variant status resolved
of reclassified variants are confirmed Benign — giving patients clarity and peace of mind
overall increase in pathogenic (P/LP) calls — more patients receiving definitive, actionable results
projected VUS resolution as the dataset grows toward 2 million participants (estimate based on current classification trends; actual results may vary)
Everything you expect, and just a little bit more
From ordering to results to follow-up — Helix handles the complexity so you don't have to.
Effortless test ordering
Order from a comprehensive genomic testing menu directly within your EHR or through our portal. No faxes, no paper, no friction required — just the right test for the right patient at the right time.
Rapid, actionable results
Receive clear, clinician-friendly results with embedded decision support. Our Sequence Once, Query Often® model delivers pharmacogenomic results in minutes, not weeks.
Seamless EHR integration
Helix integrates with Epic® so genomic insights appear right where you practice — no extra logins, no context switching.
Clinical decision support
Review evidence-based information to support your clinical judgement, whether it's considering a medication adjustment, referring to a specialist, or initiating cascade screening.
Patient engagement tools
Helix provides patient-facing materials and genetic counseling support so your patients understand their results and feel empowered to act on them.
Comprehensive test menu
From hereditary cancer and cardiovascular risk to pharmacogenomics and carrier screening — access a broad, clinically validated testing menu on a single platform.
How it works
Genomic testing integrated into your clinical workflow — from identification to action in four simple steps.
Identify the right patient
Clinical decision support flags patients who meet guideline-based criteria for genomic testing, surfaced for clinician review within your normal workflow.
Order with confidence
Select from a curated test menu with clear indications, expected turnaround, and patient cost transparency — from your EHR or our portal.
Review actionable results
Receive structured results with clinical context, pharmacogenomic information, and referral guidance — designed to support clinicians with any level of genetics expertise.
Close the loop
Configurable follow-up pathways help facilitate connection of patients with actionable findings to genetic counseling, specialist care, or cascade screening at the clinician’s direction.
Get to clinical value faster
Helix's unique Sequence Once, Query Often® approach accelerates speed to clinical value and patient insights. Our CLIA/CAP accredited lab, proprietary Exome+® assay, and advanced analytics capabilities enable rapid results delivery - from weeks to hours (or even minutes in some cases!). This speed and comprehensiveness reflects Helix’s commitment to advancing precision medicine.
Existing Patient (SOQO)®
≤ 5 days
New Patient
6–21 days
Saliva, Blood, Buccal
Go deeper
Explore the science behind our platform and the clinical programs that put genomic insights into action.
"I am thrilled with the ease of ordering and rapid nature of diagnostic resulting with Helix. Tuesday evening, I was asked to help with a case of triple negative breast cancer in a GenoWell negative screened patient and ordered the diagnostic panel Wednesday afternoon, it's Thursday morning and I already have results. Very meaningful, especially in surgically urgent cases!"
Ready to get started with a new kind of lab?
Whether you're new to genomic testing or ready to scale, Helix makes it easy to get started.