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Helix Genomic Advantage™

Build a healthier future for you and your family through no-cost genetic testing. Learn your genetic risk for cancers, heart conditions, and medication response — and get more personalized care.

  • No-cost genetic testing — Eligible members receive genetic testing at no cost — removing barriers to precision care.
  • Cancer & cardiac risk — Learn genetic risk for hereditary cancers, heart conditions, and familial hypercholesterolemia.
  • Medication response — Pharmacogenomic insights help optimize medications and avoid adverse drug reactions.
  • Personalized care plans — Results empower providers and patients to make proactive, evidence-based decisions together.

$5-10M in overall savings

Examining projected savings across a 200K member community hospital over 5 years

Drive outcomes and reduce cost with genomic insights

Eliminate High Per-Test Costs

Ongoing appropriate clinical testing with Sequence Once, Query Often® technology — one sample, a lifetime of value.

Projected Savings, Today

Predictable member-based pricing that aligns Helix's digital genomic capabilities to risk-entities.

Maximize Clinical ROI

Target high-value, high-ROI programs that make sense for your population and deliver measurable outcomes.

Administrative Simplicity

Remove admin burden and cost, simplify provider workflow, and eliminate patient co-pays.

Population-scale RWE that makes results more actionable

Real-world evidence (RWE) from the Helix Research Network, built on Exome+® sequencing across 400,000+ participants across ~20 health systems, enables us to resolve variants of uncertain significance (VUS) that would leave clinicians and patients without clear answers in other settings.

With every new patient sequenced, the evidence base deepens, making results more definitive and actionable for each next patient. The Helix approach to genomics is a continuously improving evidence engine — and every partner and provider not only benefits from that engine, they help it evolve.

45%

of VUS carriers in the general population can now have their variant status resolved

96%

of reclassified variants are confirmed Benign — giving patients clarity and peace of mind

9%

overall increase in pathogenic (P/LP) calls — more patients receiving definitive, actionable results

60%

projected VUS resolution as the dataset grows toward 2 million participants

Barrett KM, Ferber MJ, Candille S, et al. From uncertain to actionable: significant reduction in variants of uncertain significance in hereditary germline testing via multi-institutional real-world evidence. medRxiv. 2025. doi:10.1101/2025.08.12.25333547 (opens in a new tab)

Your path to value

Year one savings. Hiding in plain sight.

Aligning Helix's digital genomic capabilities to risk-entities for predictable, measurable cost reduction.

01

Population Risk Analysis

Helix performs a gratis analysis of your risk-entity population to determine year-one and four-year cost savings potential.

02

Program Design & Alignment

We align genomic testing programs to your highest-value clinical areas — oncology, cardiology, pharmacogenomics, and more.

03

Seamless Deployment

Integrate with existing EHR workflows and launch with predictable member-based pricing — no per-test cost surprises.

04

Ongoing Value with SOQO®

Sequence Once, Query Often® unlocks continuous value from a single sample — new panels, new insights, no re-collection.

05

Measurable Outcomes

Track clinical ROI, risk reduction, and cost savings with transparent reporting and ongoing optimization.

Get started today

Receive a gratis analysis.

For organizations that take on risk — whether your employee population or ACO — Helix can perform an analysis to determine your cost savings, both year one and over four years, to understand the impact Genomic Advantage® can have on your organization today.

1

Year 1 Savings

Immediate cost reduction from targeted genomic programs

2

4-Year Projection

Compounding value as SOQO® unlocks new clinical insights

3

Population Shift

Move your total population from high-risk to lower-risk categories

"We’re very excited about what’s called Helix Genomic Advantage. As a benefit to anyone who has our insurance plan, they now can at no cost avail themselves of any of the genetic testing that’s on Helix’s menu. And that is a huge, huge advantage, which is why we call it Genomic Advantage."
CC
Dr. Christopher Chapman
Network Chairman, Pathology, SLUHN

Ready to unlock genomic value?

Connect with our team to learn how Genomic Advantage® can drive measurable outcomes and reduce costs for your organization.