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Helix GenoSphere

Accelerating Precision Therapeutic Development with Clinico-Genomics

Introducing GenoSphere™, our centralized research data ecosystem built on deep genetic and longitudinal clinical data designed to optimize research and precision medicine development

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Curated, longitudinal clinico-genomic cohorts to drive research and clinical development

Our comprehensive GenoSphere™ multimodal datasets are built on the world's most dynamic precision clinical research network with longitudinal clinical data and cutting-edge Exome+® sequencing from a diverse population of >300k records from a range of therapeutic areas including Autoimmune, Cardiovascular, Metabolic and much more. Our solutions are paired with world-class translational research expertise and an AI-enabled digital cohort builder tool, Explorer™ to support life science research and clinical development across the drug development lifecycle.

Curated

Built on 13+ years of longitudinal data across major therapeutic areas including CVRM, autoimmune, and more

Unified & Timely

Whole exome sequencing, linked to OMOP harmonized longitudinal clinical data (refreshed quarterly), enriched with medical, pharmacy, and mortality claims data

Data Expertise

In-house team of experts to drive innovation with clinico-genomic data while ensuring integrity, accuracy and reliability

GenoSphere™ Highlights

>300k

longitudinal clinico-genomic records with consent for recontact

~13 years

average longitudinal patient EHR history

2x growth

in network participants size in the last 12 months

>1M participants

Targeting >1M participants across North America by 2027

GenoSphere™ multimodal Research-Ready Cohorts

Providing deep insights from genetic and real-world data across a range of therapeutic areas to advance biomarker discovery, stratify patient populations, evaluate therapeutic efficacy and much more

01

Autoimmune

Consisting of >35K individuals with conditions such as Lupus, Rheumatoid Arthritis, IBDs and more

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02

CVRM (Cardiovascular, Renal, Metabolic)

Over 165K patients with cardiovascular, metabolic and renal conditions

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03

GLP-1 Receptor Agonists

World's largest specialized GLP-1 cohort consisting of over >35k patients on major GLP-1 agonists including Semaglutide, Tirzepatide and more

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04

NASH/MASH

Cohort coming soon.

A Selection of Our Partners

Cone Health
HealthPartners
MUSC Logo
Memorial Hermann
Nebraska Medicine
Providence Logo
Renown Health logo
Sanford Health Logo
St Luke's University Health Network logo
WellSpan Health Logo
tOSU Wexner Medical Center logo
WakeMed Logo
TriHealth Logo
Parkview Health Logo
Rochester Regional Health logo

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