Genomic Analysis with Helix Explorer™
From question to answer, faster.
Explorer is Helix's clinico-genomic research platform. It brings genomic cohort building and discovery, population-scale genomic analysis, and AI assistance into one governed environment. Explorer enables our partners to manage program operations and gather key insights. The platform enables your team to move from question to answer without waiting in a bioinformatics queue or standing up in a separate technical environment.
Overcome clinico-genomic bottlenecks in one platform
Today researchers need to navigate disconnected software systems, wait months on bioinformatics queues, and clear strict compliance hurdles just to assemble a single research-ready cohort. Explorer unifies these fragmented workflows into a single clinco-genomic analysis platform. Connected to GenoSphere, Explorer gives researchers access to a 560,000+ sample clinico genomic dataset linked to longitudinal EHR records and claims, ushering in a new way to build and analyze genomic cohorts.
One Unified Platform
Today, sequencing, EHR, and claims data sit in separate silos. Datasets require months of engineering resources to build. Explorer unifies these assets, allowing researchers to discover populations and execute genomic analysis end-to-end without transferring data or switching solutions.
Self-Serve Genomic Cohort Building
Bioinformatics backlogs create compounding delays. Explorer enables self-serve genomic cohort building with no-code interfaces and natural language querying, turning months of waiting into minutes.
Population Scale Genomic Analysis
Legacy infrastructure isn't keeping up with science. Genomic-scale work makes variant analysis slow and costly. Built on Databricks Unity Catalog, Explorer delivers high-performance population scale genomic analysis with prebuilt workflows for GWAS, PheWAS, and gene burden testing.
Governed Genomic Trusted Research Environment
Creating compliant environments is slow and complex. Explorer provides a hosted genomic trusted research environment with built-in-role-based access controls, audit logging, and row-level security from day one.
One environment for every stage of research
Explorer houses the applications your team needs to go from cohort to insight, without leaving the platform.
Genomic Cohort Building: Helix Cohort Builder
No-code and AI-assisted cohort creation. Streamline genomic cohort building to create a research-ready cohort in minutes using demographic, clinical, and genomic criteria, or describe your population in plain language.
Read moreGenomic Analysis: Research Workspaces (TRE)
A purpose-built Trusted Research Environment on Databricks for population-scale genomic analysis, GWAS-style studies, and custom notebooks, with an AI coding assistant built in.
Read moreStudy Manager
HRN operations and reporting: consent tracking, enrollment, and program participation, turned into measurable, reportable value.
Built on GenoSphere™, one of the largest clinico-genomic datasets
Every application inside Explorer runs on GenoSphere, Helix's clinico-genomic dataset built on the Helix Research Network (HRN) — our network of partner health systems supplying consented, longitudinal clinical data.
- 560,000+
- paired Exome+® samples and growing
- 13+
- years of average linked EHR history
- OMOP-native, analysis-ready.
- structure for governed, on-demand analysis
Health Systems
Self-serve access to your own population's data and broader HRN data for population health and precision medicine research.
Life Sciences & Pharma
Access to GenoSphere data to support target discovery, patient stratification, and trial feasibility, without bringing external data in.
Academic & Independent Researchers
On-demand access to population-scale clinical and genomic data, coming later this year through a subscription model.
Governance built in from day one
Explorer is compliance-ready architecture, not something bolted on after the fact.
Trusted Research Environment
Built on Databricks Unity Catalog with row-level access controls and full audit trails.
Data Stays Governed
Data stays inside Helix's governed environment — compliance-ready architecture, not something bolted on after the fact.
Role-Based Access Controls
Permissions that map to your organization's existing research permissions.
Ready to see what Explorer can do for your research?
Connect with our team to see how Explorer can accelerate your research, from cohort to insight.