Pharmacogenomics (PGx) Fluoropyrimidines DPYD Test
A targeted pharmacogenomic test evaluating the DPYD gene to predict fluoropyrimidine treatment efficacy and side effect risk, powered by the Helix Exome+® platform.
Turnaround
6-9 days
Requery (SOQO)
≤ 5 minutes
Genes Tested
1
Panel Description
This test evaluates 1 gene associated with response to certain medications including fluoropyrimidines. Results from this test may help in predicting treatment efficacy and risk of side effects for these drugs.
Order This Test
Contact our clinical team to order this panel or learn more.
Indications for Testing
Patients in whom fluoropyrimidines are being considered, have been ineffective, or caused side effects.
Methodology
This test utilizes next-generation sequencing to determine star alleles and metabolizer status for DPYD.
Technical Specifications
Reportable range
DPYD: *1, *2A, *3, *4, *6-*8, *9B, *10-*13, HapB3, rs150036960, rs72549310, rs80081766, rs150385342, rs141462178, rs200562975, rs2297595, rs139834141, rs6670886, rs115232898, rs72549308, rs72549307, rs45589337, rs146356975, rs150437414, rs145112791, rs201018345, rs183385770, rs143154602, rs72549305, rs75017182, rs140602333, rs143815742, rs61622928, rs200064537, rs764666241, rs142512579, rs186169810, rs72975710, rs144395748, rs57918000, rs199549923, rs72549304, rs111858276, rs138391898, rs148994843, rs190951787, rs142619737, rs201615754, rs59086055, rs138616379, rs145773863, rs147601618, rs17376848, rs3918289, rs55971861, rs138545885, rs137999090, rs145548112, rs146529561, rs60511679, rs112766203, rs56005131, rs199634007, rs200687447, rs60139309, rs201035051, rs55674432, rs147545709, rs67376798, rs141044036, rs145529148, rs72547602, rs72547601, rs202144771, rs139459586, rs140114515, rs148799944, rs114096998
Genes Tested
1 genes included in this panel
Ordering Information
Turnaround Time
Typically 6-9 days (standard), Typically ≤ 5 minutes (requery)
Preferred Specimen
BD Vacutainer Whole Blood K2 EDTA Collection Tube 4mL or Oragene Dx Saliva Collection Kit
Shipping Instructions
Specimens to arrive at Helix within 96 hours of collection at ambient temperature.
Clinical Description
This test evaluates 1 gene associated with response to certain medications including fluoropyrimidines. Results from this test may help in predicting treatment efficacy and risk of side effects for these drugs.
Ready to order this test?
Contact our clinical team to order the Pharmacogenomics (PGx) Fluoropyrimidines DPYD Test for your patients.