Factor V Leiden and Factor II (Prothrombin) Variant Test
A targeted diagnostic test analyzing specific variants in F5 and F2 associated with thrombophilia, powered by the Helix Exome+® platform.
Turnaround
6-21 days
Requery (SOQO)
≤ 5 days
Genes Tested
2
Panel Description
Helix Factor V Leiden and Factor II (Prothrombin) Variant Test is a diagnostic test that analyzes one variant in F5 and one variant in F2 associated with factor V Leiden-related thrombophilia or prothrombin-related thrombophilia.
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Contact our clinical team to order this panel or learn more.
Indications for Testing
A relevant personal and/or family history suggestive of factor V Leiden-related thrombophilia or prothrombin-related thrombophilia.
Methodology
This test utilizes next-generation sequencing to detect single nucleotide variants.
Technical Specifications
Analytical sensitivity (SNV)
> 99%
Gene notes
F2: analysis is limited to NM_000506.5:c.*97G>A. F5: analysis is limited to NM_000130.5:c.1601G>A (p.Arg534Gln).
Genomic build
GRCh38
Genes Tested
2 genes included in this panel
Ordering Information
Turnaround Time
Typically 6-21 days (standard), Typically ≤ 5 days (requery)
Preferred Specimen
BD Vacutainer Whole Blood K2 EDTA Collection Tube 4mL or Oragene Dx Saliva Collection Kit
Shipping Instructions
Specimens to arrive at Helix within 96 hours of collection at ambient temperature.
Clinical Description
Helix Factor V Leiden and Factor II (Prothrombin) Variant Test is a diagnostic test that analyzes one variant in F5 and one variant in F2 associated with factor V Leiden-related thrombophilia or prothrombin-related thrombophilia.
Ready to order this test?
Contact our clinical team to order the Factor V Leiden and Factor II (Prothrombin) Variant Test for your patients.