Recall-by-Genotype (RbG)
Accelerating life sciences research with genetics-based recall and follow-up. Built on our deeply curated Helix GenoSphere™ clinico-genomic records, Helix’s RbG solution enables life sciences to gain a better understanding of genotypic driven phenotypic responses in a wide range of therapeutic areas.
- Build and define genetic & phenotypic criteria — specify target genes, variants, inheritance model, or polygenic thresholds aligned to your study objectives
- Assess feasibility — estimate cohort size and stratification options (e.g., ancestry, age, phenotype signals) to inform protocol design
- Recall and consent — initiate participant engagement and consent flows appropriate for required follow-up activities within the study parameters
- Collect data and generate evidence — enable additional phenotyping, surveys, or clinical assessments to analyze outcomes and study progression
Driving a genotype first approach to precision medicine development
Identifying and linking specific genetic variants to phenotypic responses in a diverse population is crucial for precision medicine development. Helix utilizes deep genomic data from over >400K linked clinico-genomic records to help researchers advance understanding of human biology and genetics.
Precision genomic targeting
Identify and recall participants based on specific genotypes, variants, or genetic profiles with unparalleled accuracy and speed.
Faster re-contact and recruitment
Reduce screen-fail and shorten timelines with focused outreach on participants most likely to qualify with full consent for recontact.
Built for life sciences
Enable biomarker and target validation, clinical trial recruitment, and rare disease cohorts from the same multi-site network protocol.
Deep clinico-genomic records
Leverage over 400K linked clinico-genomic records to identify genetic factors associated with diseases and advance understanding of human biology.
How Recall-by-Genotype works
A streamlined process to identify, recall, and study targeted populations using genetics-first precision approaches.
Define Genetic & Phenotypic Criteria
Specify target genes, variants, inheritance model, or polygenic thresholds aligned to your study objectives.
Assess Feasibility
Helix estimates cohort size and stratification options (e.g., ancestry, age, phenotype signals) to inform protocol design.
Recall and Consent
Helix works with partners to initiate participant engagement and consent flows appropriate for required follow-up activities within the study parameters.
Collect Data and Generate Evidence
Enable additional phenotyping, surveys, or clinical assessments, to analyze outcomes and study progression.
From genotype to discovery.
Recall-by-Genotype pairs world-class genomic data with targeted participant engagement, enabling life sciences researchers to validate biomarkers, optimize clinical trials, and accelerate rare disease research — all from one integrated platform.
Ready to accelerate your research?
Connect with our team to learn how Recall-by-Genotype can power your biomarker discovery, clinical trial recruitment, and precision medicine development.