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Helix GenoSphere™

Introducing GenoSphere™, our centralized research data ecosystem built on deep genetic and longitudinal clinical cohorts encompassing EHR and claims data, designed to optimize research and precision medicine development for a wide range of therapeutic areas.

  • Centralized research data ecosystem built on deep genetic and longitudinal clinical cohorts
  • Cutting-edge Exome+® sequencing linked to OMOP-harmonized longitudinal clinical data
  • Multimodal datasets spanning EHR and claims data across major therapeutic areas
  • AI-enabled digital cohort builder tool, Explorer™, for streamlined research workflows
  • In-house translational research expertise to drive innovation with clinico-genomic data

GenoSphere™ Cohort Growth

Year-over-year record growth across therapeutic areas (in thousands)

Curated, longitudinal clinico-genomic cohorts to drive research and clinical development

Our comprehensive GenoSphere™ multimodal datasets are built on the world’s most dynamic precision clinical research network with longitudinal clinical data and cutting-edge Exome+® sequencing from a diverse population of >400K records from a range of therapeutic areas.

Curated

Built on an average of 13+ years of longitudinal data across major therapeutic areas including CVRM, autoimmune, and more.

Unified & Timely

Whole exome sequencing linked to OMOP-harmonized longitudinal clinical data, refreshed quarterly, enriched with medical and pharmacy claims data.

Data Expertise

In-house team of experts to drive innovation with clinico-genomic data while ensuring integrity, accuracy and reliability.

Explorer™ Powered

AI-enabled digital cohort builder tool to rapidly identify, stratify, and analyze patient populations across therapeutic areas.

Therapeutic Areas

Access multimodal research-ready cohorts

Providing deep insights from genetic and real-world data across a range of therapeutic areas to advance biomarker discovery, stratify patient populations, evaluate therapeutic efficacy and much more.

01

Autoimmune

Consisting of >48K individuals with conditions such as Lupus, Rheumatoid Arthritis, IBDs and more.

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02

CVRM (Cardiovascular, Renal, Metabolic)

Over 230K patients with cardiovascular and metabolic conditions.

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03

GLP-1 Receptor Agonists

World’s largest specialized GLP-1 cohort consisting of >54K patients on major GLP-1 agonists including Semaglutide, Tirzepatide and more.

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04

MASH / MAFLD

Curated, longitudinal MASH-enriched cohort of over 25K linked clinico-genomic records.

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From data to discovery.

GenoSphere™ pairs world-class translational research expertise with an AI-enabled digital cohort builder tool, Explorer™, to support life science research and clinical development across the drug development lifecycle — from target identification and biomarker discovery to clinical trial optimization.

Genomic Data
Clinical Records
Drug Discovery
Accelerating precision therapeutic development

Ready to accelerate your research?

Connect with our team to learn how GenoSphere™ can power your biomarker discovery, clinical trial design, and precision medicine development.