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Helix Precision Pathway™

Seamlessly integrate genomics into clinical workflows, enhancing patient care and operational efficiency while improving access to genetic insights. Take your place at the forefront of precision medicine and transform the future of healthcare delivery.

  • EHR-embedded ordering — Clinicians order the right test at the right time, triggered by clinical criteria within their existing workflow.
  • Clinical decision support — Structured results with actionable recommendations aligned to current clinical guidelines.
  • Provider education & training — Targeted education modules and best practices to ensure confident adoption across your organization.
  • Cross-specialty standardization — Consistent genomic care across oncology, cardiology, primary care, and more.

Partner's PGx pathway drives # of patients with insights on their ability to effectively metabolize Clopidogrel

BPAs in Cardiology

for current prescribers of Clopidogrel

BPAs in Neurology

with comprehensive staff training

Post-cath lab order set

PGx pre-checked

Reimagining Healthcare Delivery Through Genomics

Integrating genomics into your healthcare delivery isn’t just about staying current — it’s about leading the way in patient care.

Personalize Patient Care

Harness genomic insights to tailor treatments and interventions for individual patients. Identify risk factors earlier, inform prediction of treatment responses, and create personalized care plans across your organization.

Streamline Clinical Processes

EHR workflow integration simplifies clinical processes and reduces patient friction. An easy-to-use portal enables a quick start, with efficient resource allocation and targeted education modules.

Enable Clinical Impact

Implement universal hereditary testing programs and personalized treatment plans. Track performance metrics and ROI with dynamic dashboards to continuously optimize care initiatives.

Comprehensive Transformation

Go beyond traditional genomic testing with EHR enablement, medical education, and real-time insights — identifying opportunities, implementing workflows, and enabling continuous improvement.

Population-scale RWE that makes results more actionable

Real-world evidence (RWE) from the Helix Research Network, built on Exome+® sequencing across 400,000+ participants across ~20 health systems, enables us to resolve variants of uncertain significance (VUS) that would leave clinicians and patients without clear answers in other settings.

With every new patient sequenced, the evidence base deepens, making results more definitive and actionable for each next patient. The Helix approach to genomics is a continuously improving evidence engine — and every partner and provider not only benefits from that engine, they help it evolve.

45%

of VUS carriers in the general population can now have their variant status resolved

96%

of reclassified variants are confirmed Benign — giving patients clarity and peace of mind

9%

overall increase in pathogenic (P/LP) calls — more patients receiving definitive, actionable results

60%

projected VUS resolution as the dataset grows toward 2 million participants

Barrett KM, Ferber MJ, Candille S, et al. From uncertain to actionable: significant reduction in variants of uncertain significance in hereditary germline testing via multi-institutional real-world evidence. medRxiv. 2025. doi:10.1101/2025.08.12.25333547 (opens in a new tab)

Clinical innovation with advanced genomics

Your partner in precision medicine transformation.

We work hand-in-hand with your team to ensure a smooth and effective implementation of genomics into your clinical practice and strategic initiatives.

01

Tailored Implementation

We assess your current workflows and design a genomic integration plan that aligns with your specific needs and goals.

02

Comprehensive Training

Our team provides thorough education and support to your staff, ensuring they’re confident in utilizing genomic insights in clinical practice.

03

Seamless EHR & Portal Integration

Genomic data is readily accessible in the format you need, supporting informed decision-making at the point of care.

04

Ongoing Performance Analysis

Tools and support for continuous monitoring of genomic program performance, helping you track improvements and identify areas for optimization.

05

Scalable Solutions

Our platform grows with your needs, supporting your organization as you expand your precision medicine initiatives across specialties.

Case study

Precision Pathway in action

What does this look like in practice? Consider this case study from a current Helix partner:

  • PGx integrated directly into the cardiac catheterization orderset, with Clopidogrel pharmacogenomics pre-checked by default.
  • Three phases — cardiology BPAs, neurology BPAs with dedicated staff training, then post-cath order set integration — each expanded weekly patient volumes.
  • The shift to neurology BPAs drove a 5.6x increase in weekly reach. Pre-checking PGx in the order set pushed that a further 65%, averaging 13.4 patients per week.
  • The result: 140 patients across 23 weeks and a 15x lift in weekly reach from baseline to peak.

Partner's PGx pathway drives # of patients with insights on their ability to effectively metabolize Clopidogrel

BPAs in Cardiology

for current prescribers of Clopidogrel

BPAs in Neurology

with comprehensive staff training

Post-cath lab order set

PGx pre-checked

Ready to add precision pathways?

Empower your organization to drive precision medicine initiatives, improve patient outcomes, and lead in healthcare innovation.