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Research Workspaces: a Trusted Research Environment for genomic analysis

Helix Research Workspaces is a Trusted Research Environment (TRE) inside Helix Explorer™, offering a purpose-built application for population-scale clinicogenomic analysis. It gives research teams secure, governed access to compute, store, and analyze more than 560,000 linked clinicogenomic records. Research teams no longer need to stand up separate technical infrastructure for every project. Built natively on Databricks®, Helix Research Workspaces gives your genomic research infrastructure a credible foundation from day one.

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560,000+ linked clinicogenomic records. Governed. Ready to analyze.
Why it exists

Genomic-scale research outgrew standard software solutions.

Population-scale genomic research often requires navigating fragmented data and specialized technical infrastructure before a single question gets answered. Variant analysis and cohort stratification can be slow and often out of reach without dedicated bioinformatics support. And pharma and health system partners need governed, audit-ready environments.

Research Workspaces closes that gap with cloud computing in genomics. Built on Databricks, it gives research teams a secure trusted research environment.

Everything a research team needs to go from cohort to analysis.

Population-scale genomic analysis

Scalable compute and specialized analysis solutions for GWAS-style studies, PheWAS, and gene burden testing. Research Workspaces delivers high-performance cloud computing in genomics for large-scale genetic research.

AI-assisted coding

A context-aware coding assistant, trained on the GenoSphere. It helps researchers develop and refine analysis code faster inside their trusted research environment.

No-code data browsing

Browse structured clinical data in GenoSphere without writing a query. Streamline your research data management so teams can explore datasets and validate cohorts before running heavy compute jobs.

Collaborative research workspaces

Project-based notebooks and workspaces that let research teams collaborate easily across a unified genomic research infrastructure. Data access controls and governance come built it in.

Integrated oversight

Get real-time visibility into job status, resource usage, and compute costs. Track large analysis runs without adding secondary applications or external platforms.

How it works

Cloud computing in genomics: from proposal to analysis

01

Describe your project

Partners can submit a research proposal and workspaces needed that describe your scope and objectives.

02

We build your workspace

Our team provisions a dedicated research workspace scoped to project. You get a compliant set up with proper data access from day one.

03

Analyze in platform

Run notebooks, GWAS-style studies, and custom pipelines with an AI coding assistant, no-code data browsing, and the Research Kit at hand.

04

Monitor and collaborate

Track compute costs and job status in real time, and collaborate with your team inside the same project workspace.

Purpose-built for GenoSphere, at population scale.

Research Workspaces and Cohort Builder both run on GenoSphere, one of the world's largest linked clinicogenomics datasets, built on the Helix Research Network (HRN).

560,000+

paired Exome+® samples and growing

13+

years of average linked EHR history, enriched with medical and pharmacy claims

OMOP-native, analysis-ready.

Governed, on-demand analysis

Ready to move from cohort to deeper analysis?

Describe your research project and our team will help you get a workspace up and running.

Research Workspaces: a Trusted Research Environment for genomic analysis | Helix