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Comprehensive Lipidemia Panel

A 27-gene panel for assessing hereditary lipidemia, powered by the Helix Exome+® platform for comprehensive lipid disorder evaluation.

Turnaround

6-21 days

Requery (SOQO)

≤ 5 days

Genes Tested

27

Panel Description

This panel evaluates 27 genes associated with hereditary lipidemia.

Order This Test

Contact our clinical team to order this panel or learn more.

(855) 699-1933
clinicalsupport@helix.com

Indications for Testing

A relevant personal and/or family history suggestive of hereditary lipidemia.

Methodology

This test utilizes next-generation sequencing to detect single nucleotide variants, insertions and deletions up to 20 bp, and copy number variants in genes associated with a variety of hereditary lipidemia conditions.

Technical Specifications

Analytical sensitivity (SNV)

> 99%

Analytical sensitivity (indel)

> 99%

Analytical specificity

> 99%

CNV sensitivity (multi-exon)

> 99%

CNV sensitivity (single-exon)

> 90%

Gene notes

ABCA1: Evaluation of exon 40 will not be performed. SAR1B: Sensitivity in exon 4 may be reduced.

Genomic build

GRCh38

Genes Tested

27 genes included in this panel

ABCA1ABCG5ABCG8ALMS1ANGPTL3APOA1APOA5APOBAPOC2CETPCREB3L3CYP27A1GPD1GPIHBP1LCATLDLRLDLRAP1LIPALIPGLMF1LPLLRP6MTTPPCSK9PNPLA2PPARGSAR1B

Ordering Information

Turnaround Time

Typically 6-21 days (standard), Typically ≤ 5 days (requery)

Preferred Specimen

BD Vacutainer Whole Blood K2 EDTA Collection Tube 4mL or Oragene Dx Saliva Collection Kit

Shipping Instructions

Specimens to arrive at Helix within 96 hours of collection at ambient temperature.

Clinical Description

This panel evaluates 27 genes associated with hereditary lipidemia.

Ready to order this test?

Contact our clinical team to order the Comprehensive Lipidemia Panel for your patients.