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HELIX DIAGNOSTICS

Comprehensive Lipidemia Panel

Panel Description

This panel evaluates 27 genes associated with hereditary lipidemia.

Genes Tested (27)

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ABCA1
ABCG5
ABCG8
ALMS1
ANGPTL3
APOA1
APOA5
APOB
APOC2
CETP
CREB3L3
CYP27A1
GPD1
GPIHBP1
LCAT
LDLR
LDLRAP1
LIPA
LIPG
LMF1
LPL
LRP6
MTTP
PCSK9
PNPLA2
PPARG
SAR1B

Important Panel Information

Turnaround time: Typically 7-21 days (standard), Typically < 5 days (requery)

Preferred specimen: BD Vacutainer Whole Blood K2 EDTA Collection Tube 4mL or Oragene Dx Saliva Collection Kit

Shipping instructions: Specimens to arrive at Helix within 96 hours of collection at ambient temperature.

Hereditary lipidemias encompass several genetic disorders affecting lipid metabolism. If left untreated, these conditions lead to premature cardiovascular disease and/or cardiovascular complications. Early detection of hereditary lipidemias allows modification of lifestyle and clinical management, which can prevent or delay these complications.

All detected variants are evaluated according to American College of Medical Genetics and Genomics recommendations. Variants are classified based on known, predicted, or possible pathogenicity and reported with interpretive comments detailing their potential or known significance.

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