Platform technology
Powering modern genomic medicine
Helix combines advanced sequencing, AI-powered interpretation, and the largest clinical genomics network to deliver diagnostic answers today—and lifetime value for your patients.
Clinical-grade sequencing. Built for what comes next.
The Helix laboratory is one of the largest clinical genomics facilities in North America, processing tens of thousands of samples monthly with industry-leading turnaround times.
Exome+® Assay
Comprehensive exome with enhanced clinical regions
Multi-Modal Capability
Short-read and long-read whole genome sequencing
Sequence Once, Query Often®
One sample becomes a lifetime of queryable data
CAP/CLIA Validated
>99% sensitivity, 99% concordance
50+ AI Agents. Working in Parallel. Reasoning at Scale.
Wayfinder™ is Helix's proprietary interpretation engine—a swarm of specialized AI agents that interrogate every variant in Helix’s assay against global clinical evidence, then synthesize findings using ACMG/AMP guidelines.
Parallel Agent Architecture
Gene validity, population data, in-silico predictions, phenotype matching, literature mining, functional evidence—simultaneously
Continuous Evidence Monitoring
Daily surveillance of PubMed, ClinVar, gnomAD
Explainable Reasoning
Every classification shows its evidence chain
Expert Validation
Final review by board-certified geneticists
Millions of Lives. Powering Every Interpretation.
The Helix Research Network® is one of the largest clinicogenomic databases in existence—millions of patients with linked genomic and EHR data. When Wayfinder evaluates a variant, it queries real-world evidence: actual patient outcomes, true clinical penetrance, population-specific frequencies.
Clinicogenomic Scale
Millions of patients with exome data + longitudinal EHR
Real-World Evidence
How variants actually manifest in real patients
Population Diversity
Representative of real-world clinical populations
Continuous Enrichment
Every test strengthens the network