Platform technology
Powering modern genomic medicine
Helix combines advanced sequencing, AI-powered interpretation, and the largest clinical genomics network to deliver diagnostic answers today—and lifetime value for your patients.
Clinical-grade sequencing. Built for what comes next.
The Helix Laboratory is one of the largest clinical genomics facilities in North America, processing tens of thousands of samples monthly with industry-leading turnaround times.
• Exome+® Assay – Comprehensive exome with enhanced clinical regions
• Multi-Modal Capability – Short-read and long-read whole genome sequencing
• Sequence Once, Query Often® – One sample becomes a lifetime of queryable data
• CAP/CLIA Validated – >99% sensitivity, 100% concordance
50+ AI Agents. Working in Parallel. Reasoning at Scale.
Wayfinder™ is Helix's proprietary interpretation engine—a swarm of specialized AI agents that interrogate every variant against global clinical evidence, then synthesize findings using ACMG/AMP guidelines.
• Parallel Agent Architecture – Gene validity, population data, in-silico predictions, phenotype matching, literature mining, functional evidence—simultaneously
• Continuous Evidence Monitoring – Daily surveillance of PubMed, ClinVar, gnomAD
• Explainable Reasoning – Every classification shows its evidence chain
• Expert Validation – Final review by board-certified geneticists
Millions of Lives. Powering Every Interpretation.
The Helix Research Network® is one of the largest clinicogenomic databases in existence—millions of patients with linked genomic and EHR data. When Wayfinder evaluates a variant, it queries real-world evidence: actual patient outcomes, true clinical penetrance, population-specific frequencies.
• Clinicogenomic Scale – Millions of patients with exome data + longitudinal EHR
• Real-World Evidence – How variants actually manifest in real patients
• Population Diversity – Representative of real-world clinical populations
• Continuous Enrichment – Every test strengthens the network