Platform technology
Powering modern genomic medicine
Helix combines advanced sequencing, AI-powered interpretation, and the largest clinical genomics network to deliver diagnostic answers today—and lifetime value for your patients.
The Foundation
Clinical-grade sequencing. Built for what comes next.
The Helix laboratory is one of the largest clinical genomics facilities in North America, processing tens of thousands of samples monthly with industry-leading turnaround times.
Exome+® Assay – Comprehensive exome with enhanced clinical regions
Multi-Modal Capability – Short-read and long-read whole genome sequencing
Sequence Once, Query Often® – One sample becomes a lifetime of queryable data
CAP/CLIA Validated – >99% sensitivity, 100% concordance
The Intelligence
50+ AI Agents. Working in Parallel. Reasoning at Scale.
Wayfinder™ is Helix's proprietary interpretation engine—a swarm of specialized AI agents that interrogate every variant against global clinical evidence, then synthesize findings using ACMG/AMP guidelines.
Parallel Agent Architecture – Gene validity, population data, in-silico predictions, phenotype matching, literature mining, functional evidence—simultaneously
Continuous Evidence Monitoring – Daily surveillance of PubMed, ClinVar, gnomAD
Explainable Reasoning – Every classification shows its evidence chain
Expert Validation – Final review by board-certified geneticists
Wayfinder Core
ACTIVE_SESSION
The Data Advantage
Millions of Lives. Powering Every Interpretation.
The Helix Research Network is one of the largest clinicogenomic databases in existence—millions of patients with linked genomic and EHR data. When Wayfinder evaluates a variant, it queries real-world evidence: actual patient outcomes, true clinical penetrance, population-specific frequencies.
Clinicogenomic Scale – Millions of patients with exome data + longitudinal EHR
Real-World Evidence – How variants actually manifest in real patients
Population Diversity – Representative of real-world clinical populations
Continuous Enrichment – Every test strengthens the network
Sequence Once, Query Often® Architecture