Dilated Cardiomyopathy Panel
A comprehensive 66-gene panel for assessing hereditary dilated cardiomyopathy and left ventricular noncompaction cardiomyopathy, powered by the Helix Exome+® platform.
6-21 days
≤ 5 days
Panel Description
Cardiomyopathies are a broad spectrum of structural and functional disorders of the heart musculature. There are many different causes of cardiomyopathies, which range from environmental exposures to inherited genetic risk factors. In cases where an external cause is not identified, and/or a family history is suspicious for hereditary risk, diagnostic genetic testing may be indicated.
This panel evaluates 66 genes associated with hereditary forms of dilated cardiomyopathy and left ventricular noncompaction cardiomyopathy.
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Indications for Testing
A personal or family history suggestive of a hereditary form of dilated cardiomyopathy and left ventricular noncompaction cardiomyopathy.
Methodology
This test utilizes next-generation sequencing to detect single nucleotide variants, insertions and deletions up to 20 bp, and copy number variants in genes associated with hereditary forms of dilated cardiomyopathy and left ventricular noncompaction cardiomyopathy.
Technical Specifications
> 99%
> 99%
> 99%
> 99%
> 90%
ALPK3: Sensitivity in exon 1 may be reduced. CDH2: Sensitivity in exon 1 may be reduced. DMD: Evaluation of chrX:33174335 (c.31+36947G>A), chrX:31261663 (c.9225-647A>G), and chrX:31261301 (c.9225-285A...
GRCh38
Genes Tested
Showing 25 of 66 genes in this panel