Associate Director, Bioinformatics

San Carlos

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We believe that everyone benefits from their biological information. It’s our mission to empower every person to improve their life through DNA. With our high-quality, trusted partners and state-of-the-art lab, we’ve created the first platform of personalized products and services powered by genetics. From inherited cancer screening to custom fitness and nutrition plans, the world of DNA learning is becoming more accessible and more valuable than ever.

So far we’ve raised over $100 million from investors like Illumina (the world’s leader in genetic sequencing equipment), Warburg Pincus, Sutter Hill Ventures, and Kleiner Perkins. Our app store and marketplace includes partners such as National Geographic, Admera Health, Vinome and many others, with whom we have partnered to develop applications which interpret your genome.

Our big vision comes with big responsibility. That’s why we’re building a team of experts in the field of genetics, engineering, design, business development, and beyond to help bring actionable insights to our customers. We’re looking for the best and brightest minds who are passionate about our mission and are excited to work on a truly diverse team.

The Helix Bioinformatics team is seeking passionate and motivated individuals to join our cross-functional team to develop and apply cutting-edge approaches to processing, analyzing, annotating, and interpreting population-scale human genome sequence data. You will work closely with lab operations, research informatics, engineering, and custom products to create our world-class genomics platform.  If you like the idea of establishing and optimizing a state-of-the-art production-scale clinical NGS-laboratory, and changing the way everyone understands their DNA, then this is the ideal opportunity for you.

As Associate Director, Bioinformatics, you will:

  • Serve as a technical lead to a team of scientists and engineers focused on creating and maintaining a robust, clinical-quality pipeline for processing high-volume next-generation sequencing data
  • Optimize performance and reliability of large-scale analysis pipelines
  • Design, implement, and test novel and reproducible NGS analysis methods
  • Migrate from R&D to production-quality code
  • Implement and document processes for regulatory purposes

Required Background:

  • PhD, MS or equivalent experience in Computer Science, Bioinformatics, or related field
  • Experience with development and management of workflows and pipelines in production environments
  • Experience with high performance computing environments and/or cloud-based environments
  • Experience with container technology such as Docker
  • Experience working with human WES or WGS data
  • Quantitative training with basic understanding of probability and statistics
  • Ability to be self-driven and work well together in a cross-functional and interdisciplinary team
  • Proficiency in Unix environments
  • Extensive programming experience in scripting languages such as Perl, Python, or Ruby
  • Familiar with application-level programming languages such as Java or C/C++
  • Experience developing APIs and SDKs
  • Responsive to feedback
  • Keen attention to detail

What Helix has to offer you

Aside from working alongside brilliant, dedicated, passionate, down-to-earth, curious, warm, and thoughtful people, we also provide great benefits:

  • Competitive compensation, including meaningful equity
  • Health insurance, including medical, dental, and vision
  • 12 weeks of Maternity or Paternity leave
  • 401(k) with employer matching
  • On-premise nursing room
  • Corporate fitness rate
  • Commuter benefits
  • Catered meals
  • Flexible PTO